BIOFREEZE spray effectively relieves pain from advanced arthritis, sore muscles, muscle spasms, strains, sprains, tendonitis, upper and lower backaches, sore joints, and will help minimize next day aches and pains. Also aids in reducing swelling and inflammation. Contains Ilex, an herbal extract for fast-acting, deep penetrating, longer lasting pain relief. Greaseless, stainless and fast-acting pain reliever! Can be used as often as necessary, up to 4 times per day. Spray it at any angle! 16 oz.